TMAO
How it works...
In fact, rapidly said, our diet contains several precursors of plasma TMAO... In fact, several N-methyl compounds found in the food (lecithin, L-carnitine,...) can reach the gut; they are here metabolized into TMA (trimethylamine) by gut microbes. Not anaybody has the same gut microbiota, so our efficiency to generate TMA is likely variable among people. This TMA is next absorbed and goes to the liver, where it is oxidized into TMAO (TMA oxide). pTMAO is next found in the plasma before being excreted by urine.