Rationale of the use of Archaeato deplete TMA in the intestine / pTMAO in plasma
Methanogenic Archaea for TMA depletion
Main advantages for the use of archaea are
- the use of TMA is essential for these life beings (methanogenesis is mandatory for these organisms),
- some of these archaea could be chosen from naturally-occuring ones in the human gut of healthy persons
- there are no known pathogens in all the domain Archaea, at least for the moment, which does not preclude that Archaea will not have bad effects / dangerous ones, but makes sense to imagine their use for human health.
- As being different from Bacteria and Human cells, we could imagine to destroy them specifically if adverse effects were seen.